Recent Publications
Wu, Q. (2005) Comparative genomics and diversifying selection of the clustered vertebrate protocadherin genes. Genetics, 169: 2179-2188 Download pdf / Supplemental Data

Zhang, T., Haws, P., and Wu, Q. (2004) Multiple variable first exons: a mechanism for cell- and tissue- specific gene regulation. Genome Research, 14: 79-89. Download pdf / Supplemental Data

Tasic, B., Nabholz, C. E., Baldwin, K. K., Kim, Y., Rueckert, E. H., Ribich, S. A., Cramer, P., Wu, Q., Axel, R., and Maniatis, T. (2002) Promoter choice determines splice site selection in protocadherin α and γ pre-mRNA splicing. Mol. Cell. 10:21-33. Download pdf

Wu, Q., Zhang, T., Cheng, J.-F., Kim, Y., Grimwood, J., Schmutz, J., Dickson, M., Noonan, J. P., Zhang, M. Q., Myers, R. M., and Maniatis, T. (2001) Comparative DNA sequence analysis of mouse and human protocadherin gene clusters. Genome Res. 11:389-404. Download pdf

Wu, Q., and Maniatis, T. (2000) Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes. Proc. Natl. Acad. Sci. USA 97:3124-3129. Download pdf

Pohl, U., Smith, J. S., Tachibana, I., Ueki, K., Lee, H. K., Ramaswamy, S., Wu, Q., Mohrenweiser, H. W., Jenkins, R. B., and Louis, D. N. (2000) EHD2, EHD3, and EHD4 encode novel members of a highly conserved family of EH domain-containing proteins. Genomics 63:255-262. Download pdf

Wu, Q., and Maniatis, T. (1999) A striking organization of a large family of human neural cadherin-like cell adhesion genes. Cell 97:779-790. Download pdf

Commented in Cell pdf, Neuron pdf, Nature neuroscience pdf, and Current biology pdf

Wu, Q., and Krainer, A. R. (1999) AT-AC pre-mRNA splicing mechanisms and conservation of minor introns in voltage-gated ion channel genes. Molecular and Cellular Biology 19:3225-3236. Download pdf

Wu, Q., and Krainer, A. R. (1998) Purine-rich enhancers function in the AT-AC splicing pathway and do so independently of intact U1 snRNP. RNA 4:1664-1673. Download pdf

Wu, Q., and Krainer, A. R. (1997) Splicing of a divergent subclass of AT-AC introns requires the major spliceosomal snRNAs. RNA 3:586-601. Download pdf

Wu, Q., and Krainer, A. R. (1996) U1-mediated exon definition interactions between AT-AC and GT-AG introns. Science 274:1005-1008. Download pdf